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15 Jan Keywords: Neuromyelitis optica, Devic’s syndrome, Devic’s disease, Myelitis, Optic La neurópticomielitis aguda (Enfermedad de Devic). En este escrito hacemos una completa revisión de la enfermedad de Devic, desde sus primeras descripciones por Eugene Devic, hasta el concepto actual. Download Citation on ResearchGate | Manejo del dolor en un caso de neuromielitis óptica (enfermedad de Devic) | Neuromyelitis optica (NMO) or Devic’s.

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However the discovery of NMO IgG antibodies directed against aquaporin-4 water channels was a critical step in such differentiation.

Conclusion and outlook The nomenclature of NMO and its atypical and abortive forms is complex. However, the lack enfdrmedad AQP4-IgG-seropositivity in a subset of patients even in the most up-to-date, recombinant assays, and in particular the demonstration of such a lack in some patients with NMO and conditions that may cause myelitis and optic neuritis by other mechanisms, e. Neurology,pp. While clinical and radiological features remain highly relevant when it comes to distinguishing seronegative NMO from MS unless a specific laboratory marker for either of these two conditions is foundthe broadening spectrum of syndromes reported associated with AQP4-IgG renders it likely that future diagnostic criteria for seropositive NMO will put less emphasis on clinicoradiological findings but rather on strict laboratory standards this could include the requirement to confirm test results in a second — and, if discrepant, a third —, methodologically independent immunoassay with high specificity and sensitivity as already recommended in devi guidelines for other autoantibody mediated diseases of the CNS.


Haykul and Michael Lechner; Neuromyelitis optica brain lesions localized at sites of high aquaporin 4 expression. Standardized method for the detection of antibodies to aquaporin-4 based on a highly sensitive immunofluorescence assay employing recombinant target antigen. Mult Scler, 9pp. Lancet,pp.

Optic neuritis and myelitis. Ueber das Zusammenvorkommen von Neuritis optica und Myelitis acuta. Lanzillotti-Buonsanti N, Pini G.

Historia de la enfermedad de Devic | Revista Colombiana de Reumatología

Brain, 59pp. Ophthalmic Review, 34pp. Waugh and Innes; Get Access Get Access.

Sensitivity, specificity, and direct comparison with immunohistochemistry. Neurology, 71pp. Recurrent optic neuromyelitis with endocrinopathies. An address on the surgical aids of medicine. Rev Med Suisse ; 3: Arch ophtalmol, 42pp. Journal List J Neuroinflammation v. J Rheumatol, 26pp. Brain magnetic resonance imaging findings in acute relapses of neuromyelitis optica spectrum disorders. J Neuro-Ophthalmol ; Brain magnetic resonance imaging abnormalities in neuromyelitis optica.

Differential diagnosis of suspected multiple sclerosis: Autoimmun Reviews ; 5: Jacob A, Bogglid M. Oxford University Press; J Fr Enferrmedad, 31pp.


Controlled pilot trial of monthly intravenous cyclophosphamide in multiple sclerosis.

The history of neuromyelitis optica

Int Rev Neurobiol Neuromyelitis optica – Devic’s syndrome, update. Frequency and prognostic impact of antibodies to aquaporin-4 in patients with optic neuritis. MRI of neuromyelitis optica: Systemic lupus Erythematosus presenting with neurological disorders.

Weill M, Gallavardin M. Plasma exchange for severe optic neuritis: Pathogenicity of patient enferedad in vivo. A clinical review and case report. MRI in the diagnosis of multiple sclerosis: Lupus, 16pp.

The history of neuromyelitis optica

Tolerability and safety of rituximab Mab- Thera. Un mes despues, sufrio empeoramiento del estado general, sindrome confusional y ceguera.

Rev Neurol Paris ; Rheumatology Oxford44pp. Acute transverse myelitis in multiple sclerosis. Arch Neurol, 65pp. In enfermevad present article, we comprehensively review the early history of NMO. Desde el descubrimiento de los anticuerpos AQ-4, ha aumentado el numero de manifestaciones clinicas y radiologicas de la NMO mas alla de la afectacion del nervio optico y de la medula espinal, entre ellas las manifestaciones cerebrales.